The structural basis for imatinib resistance in chronic myeloid leukaemia (CML) involves the emergence of imatinib-resistant BCR-ABL point mutations; mutations are usually those that impair drug ...
Abl is a non-receptor tyrosine kinase that contains a Src-homology-3 (SH3)- and a Src-homology-2 (SH2)-domain. Abl participates in many signalling pathways in the cytoplasm and the nucleus. The ...
Seit fast 100 Jahren nutzen Industrie, Handwerk und Bauwesen den SCHUKO-Stecker, den die Firma ABL im Jahre 1925 erfunden hat. Auf einer neuen Montageanlage – geliefert vom Sondermaschinenbauer AS ...
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