New practical approaches to the synthesis of complex heterocycles are reviewed. Medicinal chemistry generally involves the preparation of a lead drug candidate on a milligram scale and uses ...

The proposed method for anti-Michael addition in this study can enable one-step synthesis of α-substituted carbonyl compounds, which are commonly used in pharmaceuticals. Their study was made ...

Efficient syntheses are possible using multi-component and cross-dehydrogenative, heteroaromatic C-H silylation reactions. The structural complexity of newer small-molecule drug candidates is ...

Heterocyclic compounds are organic molecules with a ring structure comprising at least two or more elements. In most cases, these rings are composed of carbon atoms along with one or more other ...