Researchers have realized a long-held dream: inspired by an industrial assembly line, they have developed a nanoscale production line for the assembly of biological molecules. Cars, planes and many ...

Assembly-line polyketide synthases (PKSs) are homodimeric multi-enzyme systems that synthesize many structurally complex and medicinally important natural products 1,2,3,4. Their modular architecture ...

To harness the synthetic power of modular polyketide synthases (PKSs), many aspects of their biochemistry must be elucidated. A robust platform to study these megadalton assembly lines has not yet ...