T-cell profiles derived from blood and renal biopsy may be novel biomarkers of lupus nephritis treatment response, study findings suggest.

For decades, cancer immunotherapy has focused primarily on CD8 + cytotoxic T lymphocytes as the main executors of tumor cell killing. However, growing clinical and single-cell sequencing evidence ...

A review found that CD4/CD8 ratio could be used as a prognostic marker for mortality in patients with HIV, though future studies need to be done to confirm these findings. Clinical practices can ...

Researchers addressed the need for long-term expression of CCR5-specific antibodies to establish protection from HIV using ...

Obesity can leave lasting marks on immune cells, keeping inflammation active long after weight loss, new research finds.

A new EMBO Reports study suggests that obesity can leave a lasting epigenetic imprint on CD4 T cells, delaying the ...

National Institutes of Health researchers shared new details about idiopathic CD4 lymphocytopenia (ICL), a rare immune deficiency that leaves people vulnerable to infectious diseases, autoimmune ...

Among women with HIV infection, both lower CD4 counts and higher HIV RNA viral load were associated with higher incidence rates of moderate and severe cervical dysplasia, carcinoma in situ, and ...

Conservation of their respective cytoplasmic tail motifs, CxC/H in the case of CD4 and an ITIM-like motif in the case of LAG-3, supports that competition between CD4 and LAG-3 for binding of kinase ...