Pope Francis experienced two respiratory episodes Monday caused by a buildup of mucus, another setback for the Catholic Church leader as he nears his third week of hospitalization. The Holy See Press Office said the breathing setbacks were created by a buildup of mucus in the pope’s lungs and a bronchial spasm (a sudden tightening of airway muscles making breathing difficult).

Pope Francis suffered two new acute respiratory crises Monday and was put back on noninvasive mechanical ventilation, in another setback to his battle to fight pneumonia, the Vatican said. Doctors extracted “copious” amounts of mucus from his lungs during two bronchoscopies,