T cell development is a tightly regulated process that transforms immature thymocytes into mature T cells with distinct functionalities. In the thymus, precursor cells undergo a series of selection ...
Researchers at Harvard’s Wyss Institute and Tufts University have engineered frog-cell constructs that autonomously assemble ...
This biological process, where mature, specialized cells lose their distinct characteristics and revert to a more primitive, aggressive state, is a universally recognized sign of poor prognosis across ...
A cluster of recent studies has sharpened the scientific picture of how T cells switch on, tracking the molecular signals ...
For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor cell ...
Building on her discovery of the GLP-1 signaling pathway's role in sarcoma biology, Erica Pimenta, MD, PhD, of the Dana-Farber Cancer Institute, is exploring the therapeutic poten ...
Single-cell transcriptomics data from mouse bone-relevant cells was used to inform human bone mineral density genome-wide association studies and prioritize genetic targets with potential causal roles ...
The International Society for Stem Cell Research (ISSCR) is pleased to announce that Alexander Meissner, Director at the Max Planck Institute for Molecular Genetics, Germany, has been named the ...