Loss of an enzyme necessary for a process called lipoylation disrupts the way cancer cells copy their DNA, increasing their ...

Researchers at The University of Texas MD Anderson Cancer Center have developed a new imaging method, known as RF-SIRF, that ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

Inhibiting RNase H2 increases DNA damage and activates immune responses in triple-negative breast cancer, suggesting a ...

Scientists have discovered that a protein once thought to simply help load a factor necessary for the copying of DNA, actually plays a key role in ensuring fast and reliable replication—an insight ...

DNA is more than just the iconic double helix we learned in school—it's a dynamic, complex structure at the heart of life. From high-speed replication to advanced sequencing technologies, scientists ...

DNA replication is usually a very precise, templated process, but some enzymes are capable of "doodling," which might lead to ...

Drs Ursula A. Matulonis and Joyce F. Liu discuss targeting DNA damage and repair and replication stress in endometrial cancer. Drs Ursula A. Matulonis and Panagiotis A. Konstantinopoulos discuss ...