Calcium is essential for the correct functioning of the cell and requires regulation to avoid high concentrations causing cell death. Calcium ions are important for cell signaling as the binding of ...

Plasmodium falciparum causes malaria in humans by multiplying first in the liver cells and then in red blood cells. Merozoites or daughter parasites are released as the host cells are destroyed to ...

An international research team headed by scientists from Nanyang Technological University, Singapore and the Center for ...

Malaria is a serious public health burden that causes an estimated 1–2 million deaths and 300–500 million infections each year 1. There is no effective vaccine available, and parasites resistant to ...

A new approach to antimalarial development, aided by high-throughput screening, could help to overcome resistance.

Studies of 652 adults and children with acute uncomplicated falciparum malaria were done to determine the optimum treatment of multidrug-resistant Plasmodium falciparum malaria on the Thai-Burmese ...

Conversion from the asexual to the sexual phase of the malaria parasite is necessary for its transmission to the mosquito. A study led by the Barcelona Institute for Global Health (ISGlobal) -- an ...

Researchers have developed a novel approach to analyzing malaria parasite genomes to reveal how antigenic variation arises. Researchers at the European Molecular Biology Laboratory’s European ...

The opening of the Panama Canal in 1914 initiated an era in which efforts to control malaria were aimed at the anopheline mosquito. The World Health Organization's Global Malaria Eradication Campaign ...

Findings can open up new avenues for targeted approaches toward therapeutic strategies against the malaria-causing P. falciparum that are aimed at stopping the parasite's life cycle progression and ...

Drugs have been used to treat and prevent malaria for centuries. Bark from the cinchona tree, which contained an array of alkaloids with antimalarial properties, appeared in Western therapeutics in ...