Gain-of-function research (GOFR) refers to the serial passaging of microorganisms to increase their transmissibility, virulence, immunogenicity, and host tropism by applying selective pressure to a ...

In May 2025, President Donald Trump signed an executive order to restrict research on viruses and pathogens called gain-of-function studies. The National Institutes of Health is now taking steps to ...

Activists want it banned. The US government may soon further restrict it. And politicians won’t stop talking about it. So-called “gain-of-function” pathogen research has faced growing scrutiny ever ...

BELO HORIZONTE, BRAZIL - MARCH 24: Bruno Cassaro de Andrade, a chemical engineering student, works with a test during the method of separating specific proteins to be applied in the production of ...

Proteoglycans are ubiquitous molecules that function as critical components of the extracellular matrix. These proteins are composed of glycosaminoglycan chains that are covalently attached to a ...