Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.

“This is the first detailed study of how and where ORC regulates epigenetics and gene expression in human cells,” said Anindya Dutta, Ph.D., leader of the study and chair of the University of Alabama ...

DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning ...

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...

Although HPVs do express some unspliced mRNAs (Figure 2), most HPV mRNAs are the products of constitutive and alternative splicing. Constitutive splicing is where every intron in the primary RNA ...

A research team at KAIST has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation ...

Researchers developed e2MPRA, a high-throughput technique that simultaneously measures cis-regulatory element activity and ...

Oregon Health & Science University has a leading role in a new database designed to track the normal expression of genes in organs and tissues from prenatal development through adulthood. Researchers ...

Professor Carsten Carlberg has published a comprehensive new textbook, Gene Regulation and Epigenetics: How Science Works, presenting the current understanding of gene regulation and epigenomics.

This is the first detailed study of how and where ORC subunits regulate epigenetics and gene expression in human cells. “This is the first detailed study of how and where ORC regulates epigenetics and ...