A genetic difference carried by nearly one in three people may increase the risk of severe COVID-19 and lung fibrosis by ...

Germline and somatic variants are inherently connected. All germline variants originate as de novo somatic mutations either in parental germ cells or very early in embryonic development. As such, ...

Genetic divergence and adaptive variation constitute the foundation of evolutionary change in natural populations. Divergence arises when populations accumulate distinct allele frequencies through ...

Knowing how human DNA changes over generations is essential to estimating genetic disease risks and understanding how we evolved. But some of the most changeable regions of our DNA have been ...

Genome assemblies from 65 individuals, representing a variety of the world’s populations, are advancing the scientific exploration of complex genetic structural variation. Structural variations are ...

Genetic inheritance may sound straightforward: One gene causes one trait or a specific illness. When doctors use genetics, it’s usually to try to identify a disease-causing gene to help guide ...

Nomic Bio Inc. announced a research collaboration with the Wellcome Sanger Institute to perform large-scale proteomic ...

Nature and nurture both determine how likely you are to develop a particular disease. Hiroshi Watanabe/DigitalVision via Getty Images Sitting in my doctor’s examination room, I was surprised when she ...

For more than a century, Mendelian genetics has shaped how we think about inheritance: one gene, one trait. It is a model that still echoes through textbooks—and one that is increasingly reaching its ...

Gene editing may hold the key to rescuing endangered species—not just by preserving them, but by restoring their lost genetic diversity using DNA from museum specimens and related species. Scientists ...

Knowing how human DNA changes over generations is essential to estimating genetic disease risks and understanding how we evolved. But some of the most changeable regions of our DNA have been ...