Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment has been the focus of a 30-year research question. New work from the Crick ...

Every time a cell copies its DNA, parts of the genome are exposed and vulnerable to damage or errors. Molecular biologist ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

It’s tricky to make an exact copy of yourself. Or at least it is for cells undergoing mitosis, where cells replicate everything inside of them, including their neatly packaged DNA, then split in half.

Damage to DNA in cancer cells can lead to pieces breaking off chromosomes and floating away, like icebergs cracking off a glacier. Just as icebergs are a threat to ships and their crew, these ...