A worldwide study involving 12 research groups has confirmed that capillary zone electrophoresis combined with mass ...

The analytical workflow begins with the separation of the complex protein mixture, often utilizing liquid chromatography (LC) or capillary electrophoresis (CE) coupled directly to the MS system.

Mass spec–based methods coupled with chromatography separation techniques are fundamental to success in proteomics research and biopharmaceutical development, and low-flow liquid chromatography has ...

Mass spec is poised to fulfill its potential in the QC lab, say researchers who claim that a new intact protein analysis method overcomes challenges that have up to now limited adoption. Growing ...

Researchers have detailed PEPPI-MS, an experimental protocol combining high-resolution protein fractionation using SDS-polyacrylamide gel electrophoresis (SDS-PAGE) with the latest mass spectrometry ...

Nanobodies are single-domain antibodies derived from heavy-chain-only antibodies (HcAbs) commonly found in camelids, consisting solely of the variable, antigen-binding domain. Their small size affords ...

Researchers have developed a method to evaluate the folding stability of a million proteins simultaneously. DNA libraries were used to generate protein -- DNA complexes that were treated with enzymes ...

The SCIEX Echo MS+ and ZenoTOF 8600 systems redefine screening with one-second acoustic sampling and 10x sensitivity. By ...

Proteoforms, the diverse molecular variants of proteins, are key to understanding cellular functions, disease mechanisms, and ...