A new understanding of how drugs are taken in by cells could impact the way drugs are administered to patients. In an Aug. 30 study published in Nature that details structural changes of the Transient ...

Azetukalner, a Kv7 potassium channel opener, reduced the frequency of focal onset seizures by a placebo-adjusted rate of 42.7 ...

Mutated variants of a particular ion channel cause difficult-to-treat epilepsy. A study published in the journal Nature now shows that a commonly used anesthetic drug, propofol, can restore the ...

When a scrappy team of scientists joined forces in the late 1990s, they sought to identify genetic mutations that could have an outsized impact on the treatment of human disease. At the time, that ...

Epilepsy is already represented in Jazz Pharmaceuticals’ portfolio by Epidiolex, a drug that treats seizures caused by three rare types of this brain disorder. Epilepsies have many drivers, and Jazz ...

Ion channels are integral membrane proteins that regulate the flow of ions (such as sodium, potassium, calcium, and chloride) across cellular membranes. They play critical roles in numerous ...

An international team involving the Institute of Chemical Research, a joint centre of the University of Seville and the Spanish National Research Council, has developed a new technique that will ...

Ion channels are a class of transmembrane macromolecular pore proteins that enable specific types of ions to move across the cell membrane under the influence of electrochemical gradients, supporting ...