Loop diuretics are cornerstone therapies for the relief of congestion in patients with heart failure. By inhibiting the Na⁺‐K⁺‐2Cl⁻ cotransporter in the thick ascending limb of the loop of Henle, ...

To earn CME related to this news article, click here. January 28, 2009 — Prolonged use, but not ever-use, of loop diuretics is linked to a higher fracture risk in postmenopausal women, according to ...

Thirst outcomes were investigated among patients with stable heart failure (HF), due to the limited data available on this relationship and how it, along with fluid and sodium intake, influences ...

Diuretic therapy remains a cornerstone in the management of heart failure, targeting intravascular and interstitial volume overload to alleviate symptoms, improve exercise tolerance and reduce ...

CHICAGO -- The choice between furosemide and torsemide didn't matter for longer-term clinical outcomes of hospitalized heart failure patients, according to the comparative effectiveness trial ...

PRAGUE, Czechia—The number of people taking loop diuretics without a diagnosis of heart failure (HF) may be many times higher than the number of HF patients on these meds, according to an analysis of ...

Semaglutide reduces the need for loop diuretic use and dose, and has positive effects on symptoms, physical limitations, and body weight in patients with heart failure with preserved ejection fraction ...

Starting dapagliflozin (Farxiga) early during acute heart failure hospitalization didn't boost decongestion, although it appeared to spare loop diuretic doses and increase diuresis compared with usual ...

Finerenone reduced heart failure events and cardiovascular deaths in patients with HFmrEF or HFpEF when used with diuretics. The study found finerenone reduced hypokalemia risk but increased ...

LISBON — The diabetes and weight-loss drug semaglutide improves heart failure–related symptoms and physical limitations regardless of diuretic use in patients with obesity-related heart failure and ...

Uncertainty regarding diuretic efficacy and optimal dosing in hemodialysis likely contributes to practice variation, according to investigators. A new study finds “substantial” variation in oral ...