Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.

Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one has stopped using. Previously, this phenomenon was attributed to a decline ...

A new bioengineered neuronal circuit board "BioConNet" allows scientists to artificially engineer human brain-like wiring at scale and can be used to engineer any possible circuit. The fully ...

Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one has stopped using ...

The ability to measure the connectivity of each neuron in a neural circuit has established large maps of neuronal pathways—the connectome. But the extent to which those connectivity measurements alone ...

Researchers from the Vanderbilt University School of Medicine Basic Sciences have uncovered the first example of activity-dependent development of hypothalamic neural circuitry. Although previous ...

Researchers have revealed neural circuits in the brainstem that are crucially involved in implementing decisions by controlling three fundamental behavioral states or strategies: perseverance, ...

The results include a comparison between two different basis functions for temporal selectivity and how these generate different predictions for the dynamics of neural populations. The conclusions are ...

Alzheimer's disease (AD) is the most common neurodegenerative disorder, characterized by progressive cognitive decline and ...