Here, we report that glycolysis controls astrocyte-synapse contact. In the Drosophila larval dopaminergic (DAergic) circuit, blocking astrocyte glycolysis stimulated perisynaptic ensheathment by ...

Understanding how the brain works requires more than studying single regions in isolation. The cerebral cortex depends on long-distance connections that link specialized areas into coordinated ...

Researchers at UC Santa Barbara are coming ever closer to uncovering the neural circuitry that translates stimulus to action, shining light on previously unseen neural connections and lesser-known ...

Signals relayed to motor neurons from the brain enable muscle movement, but these signals typically pass through spinal interneurons before they reach their destination. How the brain and this highly ...

Scientists have identified a protective brain pathway that may help slow the progression of Parkinson's disease by strengthening the brain's own dopamine‑producing neurons, but the positive effect was ...

Alzheimer's is a devastating disease that results in memory loss and cognitive decline. It's caused by brain cells dying and the brain itself shrinking from a buildup of proteins. Millions of seniors ...

Neural circuits associated with three cortical regions in cognitive generalization with different manifestations from different species. (A) Emotionrelated brain regions mainly project to PFC and OFC; ...

This energy is critical for maintaining the connections between neurons that enable effective communication. However, in Alzheimer's disease, this essential energy production falters, leading to the ...

Stanford Medicine investigators have replicated, in a lab dish, one of the most prominent human nervous pathways for sensing pain. This nerve circuit transmits sensations from the body’s skin to the ...

Brain tumors do not just invade healthy tissue. They also physically squeeze it, and that mechanical compression may be enough to trigger neuron death in the surrounding brain. Two peer-reviewed ...