Ongoing elimination efforts have altered the global distribution of Onchocerca volvulus, the agent of river blindness, and further population restructuring is expected as efforts continue. Therefore, ...

Despite decades of research, scientists have yet to pinpoint the exact cause of nodding syndrome (NS), a disabling disease affecting African children. A new report suggests that blackflies infected ...

image: The parasite that causes river blindness infects about 37 million people in parts of Africa and Latin America, causing blindness and other major eye and skin diseases in about 5 million of them ...

Recent reports of patients failing to respond to ivermectin, the standard drug for treating river blindness (onchocerciasis), have suggested the emergence of drug-resistant Onchocerca volvulus (the ...

Onchocerciasis, or river blindness, results from infection with Onchocerca volvulus. The parasite is endemic to West Africa, in both rain forest and savanna bioclimes. Several lines of evidence ...

Moxidectin, a macrocyclic lactone, is an anthelmintic drug that selectively binds to the parasite's glutamate-gated chloride ion channels. The Food and Drug Administration (FDA) has approved ...

Microfilariae of Onchocerca volvulus obtained from onchocercomas were inoculated subcutaneously into the inguinal region of mice. Microfilariae disseminated rapidly, invading the tail and lungs within ...

Tommy Leung does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their ...