PCR-based techniques have transformed how scientists analyze transcripts’ translational applications in cancer and neuroscience research.

The detection of viable cells is pivotal in microbiology, environmental monitoring and food safety, where distinguishing live from dead organisms can significantly influence risk assessments and ...

PCR involves three core components: polymerase, primer, and template. Primers anneal to templates and create initiation sites for the polymerase. The polymerase then recruits free deoxynucleoside ...

In vitro diagnostics (IVD) is an umbrella term for tests conducted on blood or tissue samples to detect diseases, determine the efficacy of novel or established treatments, and monitor health.

When working in a lab, launching a quantitative PCR (qPCR) experiment demands a comprehensive understanding of complicated protocols, principles, and methodologies. Analyzing the large amounts of ...

Researchers have built an RT-PCR platform that gives results in 23 minutes that match the longer laboratory-based tests -- faster than other PCR tests on the market. It can be adapted to test for a ...

With the global overuse of antibiotics, the emergence of multidrug-resistant (MDR) bacteria and "superbugs" has become a major threat to human health and food safety. Among these, drug-resistant ...

A randomized trial of chemoradiation using mitomycin or cisplatin, with or without maintenance cisplatin/5FU in squamous cell carcinoma of the anus (ACT II) This is an ASCO Meeting Abstract from the ...

Digital PCR (dPCR) is a specialized approach to nucleic acid detection and quantification that is not reliant on standard curves. Instead, the quantity or numbers of molecules present in a reaction is ...

Even standard polymerase chain reaction (PCR) technology should, in principle, boost weak mutant signals so that they may emerge from all the genomic noise emitted by wild-type sequences. Yet standard ...