Depression can feel like the demands of the outside world cost you more than the resources you gain each day. You spend energy and time working, using cognitive resources to have conversations, or ...

Seasonal affective disorder (SAD) is recognized as a recurring major depressive disorder, typically starting in the fall and winter and spontaneously improving when spring arrives. It’s usually ...

NEW YORK (Reuters Health) - Maintenance therapy with the antidepressant Lexapro (also known as escitalopram) significantly reduces the risk for recurrent depression, according to study findings. Sign ...

The brains of people with recurrent depression have a significantly smaller hippocampus - the part of the brain most associated with forming new memories - than healthy individuals, a new global study ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

Summary: A Phase 2 randomized clinical trial demonstrates that a single 25 mg dose of psilocybin, combined with psychotherapeutic support, provides rapid, statistically significant, and clinically ...

A meta-analysis of studies involving over 3.2 million participants found that major depressive disorder is significantly more ...