Accurate RNA splicing is essential for gene expression and human health, yet predicting how DNA sequence variations affect splicing remains a major challenge. Although recent artificial intelligence ...

Johns Hopkins researchers have developed a powerful new AI tool called Splam that can identify where splicing occurs in genes—an advance that could help scientists analyze genetic data with greater ...

The nucleus of each of your cells contains all the genetic information (the genome) necessary to build every type of cell and protein in your entire body. Like a complex library in a tiny space 50 ...

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs -- single-stranded RNAs involved in protein synthesis -- and proteins from the same stretch of DNA, ...

Natural killer cell transcriptomic expression and prediction of survival after immune checkpoint blockade across cancers. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This ...

Although you may not appreciate them, or have even heard of them, throughout your body, countless microscopic machines called spliceosomes are hard at work. As you sit and read, they are faithfully ...