One of the most important functions of topoisomerase I is the regulation of DNA supercoiling. In fact, the DNA molecule is usually folded back on itself several times to fit inside the cell nucleus ...
BC3195, a novel ADC targeting CDH3: Preliminary results of a first-in-human phase I study in patients with advanced solid malignancies. This is an ASCO Meeting Abstract from the 2024 ASCO Annual ...
Eribulin plus pyrotinib In trastuzumab-resistant HER2-positive advanced breast cancer: A single-arm, multicenter phase II trial (EPIC trial). Association of pre-treatment HER2 amplicon mRNA signature, ...