When Daniel Fischer cofounded Tevard Biosciences in 2017, he wasn’t trying to bet on the next hot RNA technology. His interest was more personal. His daughter Natasha has Dravet syndrome, a rare form ...

Neurodegenerative diseases are commonly adult-onset conditions characterized by degeneration of specific neuronal populations. Familial forms are caused by mutations in single genes, but most patients ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

The firm's first candidate, AP003, will focus on rare genetic liver diseases caused by nonsense mutations that prematurely halt protein production.

The various identities of cells, whether they are in the brain, heart, kidney, or any other tissue, are defined by the genes they expressed. In basic terms, the genes that are active in a cell are ...

Genetic medicine has made huge progress over the past two decades. Gene therapy, gene editing, and mRNA treatments are now approved for a growing number of conditions. These approaches focus on fixing ...

A significant research paper published in the journal Cell Metabolism by the team of Prof. LIU Qiang at the University of Science and Technology of China (USTC) reveals the critical role of glutamate ...

The structure of a key enzyme involved in protein production is revealed by cryo-electron microscopy (cryo-EM). Using cryo-EM, researchers at Goethe University (Frankfurt, Germany) shed light on ...