In a prospective study of rhesus monkeys inoculated with Plasmodium coatneyi or saline on an infection/ gestational timeline, we determined the serum levels of tumor necrosis factor-α (TNF-α), soluble ...

Plasma membrane is central for homeostatic maintenance in mammalian cells. It is a direct barrier against extracellular environment; it harbors protein sensors and receptors transducing extracellular ...

Since the time of the ancient Greek physician Hippocrates, cancer has been recognized as being sensitive to heat. Today, this principle forms the basis of hyperthermia treatment—a promising cancer ...

Heat-induced increase of membrane fluidity is suppressed by cholesterol, preventing membrane disruption. Thus, cholesterol-rich cells are resistant to heat-induced necrosis, and cholesterol depletion ...

Hyperthermia, a cancer treatment using controlled heat to kill tumor cells, shows promise but faces limitations due to some tumor cells' unexpected heat resistance. Researchers from Japan have now ...