When you take a walk, talk to a friend, or chew a piece of food, motor neurons are behind these movements. Just like other parts of your body, they can become damaged. You may have heard of ALS, ...

It is easy to confuse one motor neuron disease for another: amyotrophic lateral sclerosis, primary lateral sclerosis, and lower motor neuron disease can all mimic each other. But each has a slightly ...

Areflexic, or flaccid, bladder and bowels occur when the spinal cord injury is low enough to damage the cauda equina and alpha motor neurons. It also occurs in all spinal cord injury patients during ...

A diagnosis of amyotrophic lateral sclerosis can be overlooked by clinicians unfamiliar with the various signs of the disease. ALS is purely a motor neuron disease; sensory neurons are not affected. 4 ...

Amyotrophic lateral sclerosis, already a rare condition affecting one to three people in 100,000, nonetheless garners most of the attention in the field of motor neuron disease. Those conditions that ...

Learn about motor neuron disease—its types, symptoms, causes, and treatments—to better understand how it affects movement, ...

Northwestern University scientists have identified the first compound that eliminates the ongoing degeneration of upper motor neurons that become diseased and are a key contributor to ALS (amyotrophic ...

Primary lateral sclerosis (PLS) and amyotrophic lateral sclerosis (ALS) are neurodegenerative diseases. PLS typically develops slowly, while ALS rapidly affects mobility and can become fatal.

Brian Wainger, MD, PhD, of the Healey Center for ALS at Massachusetts General Hospital (MGH) presented initial, top-level results of a recently completed phase 2 clinical trial of ezogabine (also ...