When viral DNA is more “liquidy,” it is more easily injected into host cells—so easily, in fact, that multiple virus-carrying capsids may squeeze their DNA payloads into a host cell simultaneously.

Hiding their DNA genome inside the nucleus of the infected cells, the herpesviruses establish a lifelong infection in humans. Not well defined stress conditions are known to wake up these parasites ...

Kaposi's sarcoma-associated herpesvirus (KSHV) is strongly linked to Kaposi's sarcoma, primary effusion lymphomas, and a subset of multicentric Castleman's disease. The mechanism by which this virus ...

The oncogenic herpesvirus (HHV8 or KSHV) causes a cancer known as Kaposi's Sarcoma. An international team of scientists led by the University of Helsinki has discovered key factors that control the ...

PHILADELPHIA -- Researchers have found a way to activate Epstein-Barr viruses inside tumors as a way to identify patients whose infection can then be manipulated to destroy their tumors. They say this ...

Reactivation of human cytomegalovirus (HCMV) from latency is a major health consideration for recipients of stem-cell and solid organ transplantations. With over 200,000 transplants taking place ...

Future Microbiol. 2012;7(10):1191-1205. Another viral lytic gene product, vIRF4, was recently identified to be a novel interaction partner of RBP-Jκ. vIRF4 binds the hydrophobic pocket of RBP-Jκ ...

A new study reveals how C210, a curcumin derivative, selectively reactivates Epstein–Barr virus to kill cancer cells without infectious risks, paving the way for safer, targeted cancer therapies.

New research investigating possible interactions between Epstein–Barr virus (EBV) and neurological diseases has successfully infected neuronal-like cells in vitro, with the hope to use these as a ...