Researchers used a novel phosphate-activation reagent, 2-MeImIm-Cl, in an improved coupling reaction to increase the yield of ADP- or ATP-containing molecules. Unlike traditional reactions, the ...
In a recent study posted to the bioRxiv* preprint server, researchers discovered compounds able to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) macrodomain 1 (Mac1) and ...
Purines are heterocyclic aromatic molecules that are among the oldest and most influential biochemical compounds in evolutionary history. 1 The purine nucleotide adenosine triphosphate (ATP) is the ...
Hsp90 plays a central role in cell homeostasis by assisting folding and maturation of a large variety of clients. It is a homo-dimer, which functions via hydrolysis of ATP-coupled to conformational ...
ATP-ADP exchange was estimated in the presence of plasma membrane H+-ATPase of oat (Avena sativa) roots partially purified with Triton X-100 by measuring [14C]ATP formation from [14C]ADP. Most studies ...
Adenosine triphosphate (ATP) is the essential energy molecule that drives our bodies. The cleavage of one of its three phosphate molecules releases a massive amount of energy that powers cells. The ...
ATP is the main source of energy for most cellular processes. The building blocks of ATP are carbon, nitrogen, hydrogen, oxygen, and phosphorus. Because of the presence of unstable, high-energy bonds ...
The DiscoveRx ADP Hunter™ assay measures the generation of ADP resulting from kinase phosphorylation of a substrate, in a format specifically designed for the high throughput screening laboratory. ADP ...
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