DNA scaffolds that mirror influenza virus protein geometry boost antiviral binding and reduce infection more effectively than free molecules, enabling a modular antiviral design strategy.

Unlike living organisms, to avoid extinction, viruses need to hijack living host machineries to generate new viruses. The devastating respiratory virus, influenza A virus, utilize its hemagglutinin ...

The hemagglutinin (HA) of influenza A (H3N2) virus responsible for the 1968 influenza pandemic derived from an avian virus. On introduction into humans, its receptor binding properties had changed ...

Recombinant baculoviruses (rBVs) have been extensively used to generate virus-like particles, and baculoviruses expressing antigenic proteins have become efficient tools for inducing protective ...

DURHAM, N.C. -- Duke researchers have opened a new avenue in the attack against influenza viruses by creating a vaccine that encourages the immune system to target a portion of the virus surface that ...

Vaccines now in clinical trials can raise broad-spectrum antibodies against more than one form of hemagglutinin and provide protection against the flu strains that have been most troublesome from a ...

In the spring of 2013 a strain of influenza virus that had never infected humans before began to make people in China extremely ill. Although the virus, known as H7N9, had evolved among birds, it had ...

Imagine getting your flu vaccine as a pill, in the mail. Or imagine getting just one shot that would protect you against all of the different flu strains out there. Either way, it could mean an end to ...

Cold hemagglutinin disease is a chronic hemolytic anemia that is refractory to the usual treatments for hemolytic anemia mediated by a warm-reactive antibody; it may be associated with a low-grade ...

An experimental influenza vaccine carrying more than 80,000 variations of hemagglutinin antigens caused the immune system of mice and ferrets to respond more strongly to less variable portions of the ...