Scientists have probed the molecular and cellular basis of a form of hyper IgE syndrome, a rare immunodeficiency condition that manifests as a skin and systemic allergy combined with bacterial ...

NEW YORK, Oct. 19, 2021 (GLOBE NEWSWIRE) -- Cellectis S.A. (NASDAQ: CLLS – EURONEXT GROWTH: ALCLS) (the “Company”), a gene-editing company with clinical-stage immuno-oncology programs using allogeneic ...

Autosomal-recessive hyper-IgE syndrome (AR-HIES) is a combined immunodeficiency recently found to be associated with mutations of DOCK8. Clinically, this disorder is characterized beside recurrent ...

STAT3 hyper-IgE syndrome (STAT3-HIES) patients presented with significantly lower Staphylococcus aureus-specific serum IgG compared to cystic fibrosis patients despite recurrent S. aureus infections.

Hyper-IgE syndrome (HIES) and related immune disorders constitute a heterogeneous group of primary immunodeficiencies marked by elevated immunoglobulin E levels, recurrent infections, eczema and a ...

Interleukins, small proteins that act as a biological telecommunications system, facilitate communication among leukocyte white blood cells to regulate their response to infections or nascent cancer.

Scientists have described an exquisitely balanced interplay of four molecules that trigger and govern antibody production in immune cells. As well as being an important basic science discovery, it ...

Answer::Sam, hyper-IgE or Job-Buckley syndrome is rare and I don’t know the answers to your questions. The best would be to ask you treating physician if he knows. Good luck. Discover the Truth Step ...