Recent randomized trials have profoundly reshaped the surgical management of early-stage non-small cell lung cancer. The ...
The US Food and Drug Administration (FDA) has revised a 2023 draft guidance on master protocols for drug and biological ...
Whole-blood transfusion has recently gained favor in the management of severe hemorrhage; however, data from large clinical trials evaluating its clinical effectiveness and safety are lacking. We ...
Despite guideline recommendations, evidence for the use of non–vitamin K antagonist oral anticoagulant (NOAC) monotherapy in patients with atrial fibrillation after implantation of a drug-eluting ...
Breakthrough Designation: Pivotal Trials Lack Randomization, Double-Blinding and Control Groups A review of all therapeutics receiving a breakthrough designation and approved from 2012 to 2017 found a ...
Off-label rituximab was noninferior to ocrelizumab (Ocrevus) in people with newly diagnosed relapsing multiple sclerosis (MS) and recent disease activity, the phase III OVERLORD-M ...
A New York Times health reporter explains what clinical trials are, why they are important and how they can help inform us. Credit...Ricardo Tomás Supported by By Nina Agrawal Nina Agrawal is a health ...
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