In this presentation we presented an innovative integrated system designed to automate the tangential flow filtration (TFF) process based on inline concentration measurement. This system employs ...

Monoclonal antibody (mAb) manufacturers struggling with single-use technology (SUT)-derived impurities should use ultrafiltration and diafiltration as the basis of their removal strategies, according ...

The results found that repeatability testing found all 15 processes to be with in specification for target final concentration. After using a process analytical technology (PAT)-automated tangential ...

Scaling UF/DF processes from development to manufacturing often uncovers hidden weaknesses that slow timelines, increase manual work, and add risk. These challenges usually trace back to early ...