How a superionic state enables long-term water storage in Earth's interior

The cycling of water within Earth's interior regulates plate tectonics, volcanism, ocean volume, and climate stability, ...
Oak Ridge National Lab

Ionic Pairs-Engineered Fluorinated Covalent Organic Frameworks Toward Direct Air Capture of CO2

The covalent organic frameworks (COFs) possessing high crystallinity and capability to capture low-concentration CO2 (400 ppm) from air are still underdeveloped. The challenge lies in simultaneously ...
Morningstar

U.S. FDA approves expanded indication for Lilly's Jaypirca (pirtobrutinib), the first and only non-covalent (reversible) BTK inhibitor, for adults with relapsed or refractory ...

Approval is based on results from the BRUIN CLL-321 trial, the only randomized Phase 3 study in CLL/SLL in which all patients were previously treated with a covalent BTK inhibitor This expanded ...
Phys.org

Covalent bonds found in alpha plutonium clarify its unusual atomic structure

Plutonium has captured the attention of scientists since its discovery in the early 1940s. This enigmatic element has an important role to play in emerging energy technologies like nuclear batteries ...
News Medical

Balancing speed and selectivity is key for designing effective targeted covalent inhibitors

One class of drugs that has shown promise in treating diseases ranging from lung cancer to COVID-19 are targeted covalent inhibitors (TCIs). These small molecule drugs form covalent bonds with their ...
ascopubs.org

Phase III Trial of Pirtobrutinib Versus Idelalisib/Rituximab or Bendamustine/Rituximab in Covalent Bruton Tyrosine Kinase Inhibitor–Pretreated Chronic Lymphocytic Leukemia ...

Isatuximab Subcutaneous by On-Body Injector Versus Isatuximab Intravenous Plus Pomalidomide and Dexamethasone in Relapsed/Refractory Multiple Myeloma: Phase III IRAKLIA Study Patients were randomly ...
Business Wire

Ionic Digital Reaffirms Commitment to Maximizing Stockholder Value and Opposes Self-Serving Agenda of Figure Markets and GXD Labs

AUSTIN, Texas--(BUSINESS WIRE)--The Ionic Digital Inc. (“Ionic” or the “Company”) Board of Directors (the “Board”), today issued an open letter to stockholders reaffirming its unwavering commitment to ...
Benzinga.com

Why Is Diabetes-Drug Developer Biomea Fusion Stock Trading Lower On Tuesday?

On Tuesday, Biomea Fusion Inc. (NASDAQ:BMEA) revealed topline results from the ongoing COVALENT-111 study of icovamenib in patients with type 2 diabetes (T2D). Icovamenib was investigated in three ...