They review common resistance mechanisms, such as secondary mutations (T790M, C797S), pathway activation, and histologic ...

Data demonstrate potent suppression of MAPK signaling and viability in KRAS mutant cell lines, as well as anti-tumor activity across multiple ...

Panelists discuss how understanding EGFR mutations has transformed the treatment landscape for non–small cell lung cancer ...

A mutation previously linked to skin disorders like psoriasis may also play a surprising role in gut health, according to new ...