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Many peptide hormones elicit a wide array of physiological effects by binding to G-protein coupled receptors. We have determined the conformation of pituitary adenylate cyclase activating polypeptide, ...
A Ca 2+ dependent conformational change in dimeric S100B(ββ) is required for it to bind p53 and inhibit phosphorylation of this tumor suppressor in its C-terminal negative regulatory domain. A peptide ...
*To whom correspondence should be addressed. Street address: 402 N. Blackford St., Rm. LD-154. Phone: (317) 274-6897. Fax: (317) 274-2393. E-mail: [email protected] Article Views are the ...
‡ Wuhan Center for Magnetic Resonance, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan, ...
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