Read the latest St. Louis Cardinals, Blues, Mizzou, SLU & high school sports news from the St. Louis Post-Dispatch.

Situated about halfway between Kansas City, Missouri, and Indianapolis, St. Louis overlooks the Mississippi River on the Missouri-Illinois border. Inside its 79 neighborhoods, visitors will find ...

Some research shows St. John’s wort can help treat depression and other medical conditions, but experts warn there are some downsides to this herbal supplement. St. John’s wort is natural. It’s an ...

It was a hub for riverboats, wagon trains, and the railroad, and the gateway of westward expansion. Its food and music were born of the New Orleans’ spirit. Still, the city remains underappreciated.

The building's owner attributes the receivership to challenges facing downtown St. Louis, including persistent office vacancies, safety concerns and rising costs, but he remains optimistic about the ...

The ST segment is the line between the “S” and the “T” on the readout of an EKG. If a person is in good health, the line appears at or close to the baseline level. A depressed or elevated ST segment ...