The loss was just the fifth in the past 21 games for the Astros, who had won the first two games of the series.

The Astros are heavily favored (-286 on the moneyline) when they square off against the Rockies (+230). The Houston Astros will give the start to Brandon Walter (1-1, 3.34 ERA), who is looking for win No.

However, Alvarez, who was ramping up and expected to face live pitching, has faced a setback from his hand fracture. Astros' higher-ups didn't make it sound like it was promising, with a new development coming out of Houston. According to The Athletic, Alvarez was scheduled to see a hand specialist on Wednesday.

Astros Announce Injury Update on All-Star Yordan Alvarez on Thursday originally appeared on Athlon Sports. The Houston Astros have been without one of their best players while having a seven-game lead at the top of the AL West.

Yordan Alvarez received two injections in his injured hand and will be shut down from baseball activities for "the upcoming days."

The Houston Astros placed infielder Luis Guillorme on the 10-day injured list with a strained right hamstring on Wednesday, the latest position player sidelined for the AL West leaders. The eight-year veteran Guillorme appeared in 12 games for the Astros,

D ENVER - The Houston Astros placed infielder Luis Guillorme on the 10-day injured list with a right hamstring strain before their game Wednesday against the Colorado Rockies, the team announced. Infielder Zack Short was called up from Triple-A Sugar Land to replace Guillorme on the active roster.