The San Francisco 49ers defense struggled some against the Tennessee Titans, but their offense had a huge day to mark the ...

The 49ers have to start accepting the cold, hard truth about Ricky Pearsall.

San Francisco 49ers quarterback Brock Purdy has moved into ninth in passing yards in franchise history, surpassing Frankie ...

Tennessee exposed the Niners defense; the Titans ran easily, threw over the top, hit and missed wide open receivers. Robert ...

Who can you start and sit in the fantasy football playoffs? USA TODAY Sports breaks down some top options for Week 16.

The Tennessee Titans have placed a trio of safeties on injured reserve. Tuesday's moves effectively end the seasons of Xavier ...

In that scenario, Seattle would be at 11-3 and take the No. 1 seed, while the Rams would slide to 10-4. A 49ers win over the ...

Trent Williams is one of the greatest offensive football players of all time. He deserves to score a touchdown.

That is, until now. Eddy Pineiro has been revolutionary for the 49ers and has been key to the 49ers' success this season.

According to Tom Pelissero of NFL Network, there are three different ways that the 49ers can clinch the playoffs in Week 16.

San Francisco 49ers stars Christian McCaffrey and Kyle Juszczyk both sit atop their positions in Pro Bowl fan voting.

San Francisco 49ers quarterback Brock Purdy (13) runs the ball past Tennessee Titans linebacker Cedric Gray, left, during the ...