The San Francisco 49ers defense struggled some against the Tennessee Titans, but their offense had a huge day to mark the ...

The 49ers have to start accepting the cold, hard truth about Ricky Pearsall.

San Francisco 49ers quarterback Brock Purdy has moved into ninth in passing yards in franchise history, surpassing Frankie ...

SANTA CLARA, Calif. (AP) — Brock Purdy threw three touchdown passes and the San Francisco 49ers started the stretch run of ...

Here's a look at the studs and duds (and those in between) from the Tennessee Titans' 37-24 loss to the San Francisco 49ers ...

The Tennessee Titans say the home of defensive tackle Jeffery Simmons was burglarized while he was on the road in San ...

It's clear the 49ers are relying on Pearsall to become Aiyuk's successor in the receiving corps — this season and in the ...

The Indianapolis Colts host the San Francisco 49ers on " Monday Night Football " in NFL Week 16 action. Both teams are ...

The Tennessee Titans fell to the San Francisco 49ers in Week 15 action, and here are some players whose stock rose or fell in ...

The San Francisco 49ers are playing the Tennessee Titans on Sunday, but they could benefit from some other games going ...

NBC Sports Bay Area's Matt Maiocco responds to a 49ers fan's take on if Fred Warner can return to play with San Francisco for ...

Fans planning to attend the 49ers-Titans Week 15 matchup at Levi’s Stadium on Sunday should prepare for dense fog during the ...