BACKGROUND: Oscillatory shear stress (OSS), resulting from disturbed blood flow, is implicated in atherosclerotic plaque formation by incompletely understood mechanisms. This study aims to elucidate ...

Scientists at the Max Planck Institute for Biology have discovered a remarkably streamlined strategy for developmental ...

Sanofi is tight-lipped about the future of its underwhelming pact with Denali Therapeutics after the French pharma scrapped what appeared to be the final RIPK1 inhibitor from the deal. | Sanofi is ...

First patients dosed in DAYBreak™ registrational program for bexobrutideg in relapsed/refractory CLLPresented Phase 1 results at ASH 2025 that ...

Purdue researchers identify the PACT protein as a potential target for triple-negative breast cancer, opening new paths for future treatments.

An innovative and scalable proximity labelling method profiled proteins present in the Caenorhabditis elegans brain during learning, identifying known regulators as well as novel biological pathways.

A Purdue University team led by Kyle Cottrell has discovered a new therapeutic target for triple-negative breast cancer.

Researchers at Nano Life Science Institute (WPI-NanoLSI) and the Cancer Research Institute at Kanazawa University have ...

Increasing evidence exists regarding receptor-interacting protein kinase 1 (RIPK1), a necroptosis regulator, being involved in inflammation and fibrosis in chronic liver disorders. The relationship ...

Researchers at Nano Life Science Institute (WPI-NanoLSI) and the Cancer Research Institute at Kanazawa University led have uncovered how targeted lung cancer drugs alter the shape and behavior of a ...

The development of new therapeutics targeting protein kinases is crucial in the fight against diseases like cancer.