“This is a wonderful piece of work,” said Henrik Zetterberg at the University of Gothenburg, Sweden. He was not involved in ...

Unlike other prior studies that detected changes in AD markers following COVID-19 infection ( Jan 2021 news; May 2023 ...

Both Tabrizi and Yang think that knocking down MSH3 could stave off HD pathology. Tabrizi noted that MSH3 also modifies other run-on repeats, including those causing fragile X syndrome, myotonic ...

Scientists are urgently seeking fluid biomarkers for frontotemporal dementia, the most common dementing illness among 40- and ...

In related news, other scientists recently reported that phospho-tau isoforms in the CSF mirror protofibrillar forms of tau, ...

At the Human Amyloid Imaging (HAI) meeting, held January 15-17, researchers focused on new techniques—all based on tau and ...

When it comes to tau tangles, cortical deposits receive the lion’s share of scientists’ attention, but it is the tiny subcortical regions where tangles originate that might set the course for ...

Detecting toxic forms of tau before they weave into dense thickets of tangles could pave the way for earlier diagnosis and ...

Although efforts to identify biomarkers for Alzheimer's disease are advancing rapidly, many still struggle to obtain information from populations other than non-Hispanic white people. At the Human ...

Expanded repetitive sequences are infamous for causing inherited disease. Think poly-Q tracts that cause Huntington’s or the C9orf72 hexanucleotide run-ons that trigger ALS/FTD. However, given people ...