Protein aggregation can occur due to a variety of causes. There are four classes that these causes can be categorized into, which are detailed below. Mutations that occur in the DNA …

Jul 1, 2023 · Protein aggregation studies are important to understand the mechanism behind the occurrence of various protein misfolding and aggregation diseases. Protein aggregation can …

Sep 8, 2023 · Here, we review the current understanding of how intrinsic protein conformational propensities are modulated by physiological and pathological interactions in the cell to shape …

Jul 8, 2025 · Proteins are vital for the regulation of several cellular functions, including the synthesis of structural components. The change in environmental conditions will impact …

Jul 8, 2025 · Protein aggregation refers to the spontaneous association of proteins into larger, nonnative structures, leading to the formation of aggregates with distinct physicochemical …

Jul 31, 2025 · Protein aggregation occurs when unfolded or partially folded protein molecules interact with each other, forming clusters or larger complexes. This process can be triggered …

Nov 7, 2025 · Protein aggregation is a critical phenomenon that occurs when certain proteins, rather than folding into a single, unique native conformation, adopt alternative, often misfolded …

6 days ago · Protein aggregation is the process by which misfolded proteins adopt a conformation that cause its polymerization into aggregates and organized fibrils.

The aggregation process involves several protein-protein interactions, such as hydrophobic and electrostatic interactions, which are concentration-dependent; an increase in protein …

Protein aggregation plays a central role in a wide constellation of fields, ranging from bio‐materials and biotechnology to food science, human health and physiology. Research in the area has a …