Brentuximab vedotin, sold under the brand name Adcetris, is an antibody-drug conjugate medication used to treat relapsed or refractory Hodgkin lymphoma (HL) and systemic anaplastic large cell lymphoma (ALCL), a type of T cell non-Hodgkin lymphoma.

Feb 29, 2024 · Brentuximab vedotin is used in adults and children at least 2 years old to treat classical Hodgkin lymphoma. Brentuximab vedotin is also used in adults to treat anaplastic large cell lymphoma that affects organs throughout the body (systemic) or that is confined only to the skin (primary cutaneous).

Brentuximab vedotin (BV), a potent antibody-drug conjugate, targets the CD30 antigen. Owing to the remarkable efficacy shown in CD30-positive lymphomas, such as Hodgkin's lymphoma and systemic anaplastic large-cell lymphoma, BV was granted ...

AVD: A combination of 3 chemotherapies—Adriamycin, vinblastine, and dacarbazine. ADCETRIS will not work for everyone. Individual results may vary. What is the most important serious safety information I should know about ADCETRIS?

Brentuximab vedotin is approved to treat: Anaplastic large cell lymphoma. Brentuximab vedotin is used in: Adults whose cancer is systemic and has not gotten better after treatment with combination chemotherapy. Adults whose cancer has not been treated. Brentuximab vedotin is given with cyclophosphamide, doxorubicin hydrochloride, and prednisone.

Brentuximab vedotin is indicated in adult patients for the treatment of previously untreated stage III or IV classical Hodgkin's lymphoma (cHL) in combination with doxorubicin, vinblastine, and dacarbazine.

Dec 6, 2024 · The CD30-directed antibody-drug conjugate brentuximab vedotin (BV) was FDA approved in 2011 for the treatment of relapsed classic Hodgkin lymphoma (cHL), in 2015 for maintenance after autologous transplantation in high-risk patients, and in 2018 for frontline therapy with doxorubicin, vinblastine, and dacarbazine for advanced stage cHL.

BRENTUXIMAB VEDOTIN (bren TUX see mab ve DOE tin) treats lymphoma. It works by blocking a protein that causes cancer cells to grow and multiply. This helps to slow or stop the spread of cancer cells.

Medscape - Indication-specific dosing for Adcetris (brentuximab vedotin), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and...

What is this drug used for? It is used to treat lymphoma. What do I need to tell my doctor BEFORE I take this drug? If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had. If you have any of these health problems: Kidney disease or liver disease.